We Love Science

Ep 53: Safety and Ethics in a CRISPR World

June 30, 2024 Shekerah Primus & Fatu Badiane-Markey Season 3 Episode 21
Ep 53: Safety and Ethics in a CRISPR World
We Love Science
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We Love Science
Ep 53: Safety and Ethics in a CRISPR World
Jun 30, 2024 Season 3 Episode 21
Shekerah Primus & Fatu Badiane-Markey

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In this episode of "We Love Science," hosts Shekerah and Fatu delve into the safety and ethical considerations surrounding CRISPR gene editing technology. Joined by special guest, Irina Gostimskaya, we explore the complexities and implications of advances in biomedical technology, including the use of CRISPR in humans. 

The main purpose of ethical guidelines in biomedicine is to protect patients and ensure responsible scientific conduct. Past abuses of biomedical technology including inhumane medical experiments set the stage for modern bioethics. Key moments that shaped current ethical guidelines include: the 1947 Nuremberg Code developed after the trial of Nazi doctors, and the 1978 Belmont Report issued in response to an unethical Syphilis study conducted on African American men. 

Throughout the decades, groundbreaking advancements in biotechnology have compelled the scientific community to unite in discussion to create new guidelines for their responsible and ethical use. The advent of CRISPR genetic engineering has been met with the same commitment to responsible application of the technology and ethical biomedical conduct.

Tune in to learn about:

·       Historical context of Bioethics

·       Safety concerns with DNA manipulation

·       CRISPR-specific safety issues

·       Ethical challenges with CRISPR gene editing

·       The CRISPR babies scandal

 

Catch up on the previous CRISPR episodes:

·       Ep 35: The first CRISPR Chronicles episode: How CRISPR gene therapy is bringing hope to the world

·       Ep 38: A foundational discussion explaining the secret behind CRISPR gene therapy 

·       Ep 41: A look into the ups and downs of how the CRISPR saga developed

·       Ep 47: The CRISPR Cure for Sickle Cell Disease

·       Ep 50: CRISPR clinical trials 

 

And you may also enjoy: 

Reach out to Irina: gostimskaya@gmail.com

Reach out to Fatu:
www.linkedin.com/in/fatubm
Twitter: @thee_fatu_b
and LoveSciencePodcast@gmail.com

Reach out to Shekerah:
www.linkedin.com/in/shekerah-primus
and LoveSciencePodcast@gmail.com


Music from Pixabay: Future Artificial Intelligence Technology 130 by TimMoor
Music from https://freemusicarchive.org/music/Scott_Holmes: Hotshot by ScottHolmesMusic

Show Notes Chapter Markers

Send us a Text Message.

In this episode of "We Love Science," hosts Shekerah and Fatu delve into the safety and ethical considerations surrounding CRISPR gene editing technology. Joined by special guest, Irina Gostimskaya, we explore the complexities and implications of advances in biomedical technology, including the use of CRISPR in humans. 

The main purpose of ethical guidelines in biomedicine is to protect patients and ensure responsible scientific conduct. Past abuses of biomedical technology including inhumane medical experiments set the stage for modern bioethics. Key moments that shaped current ethical guidelines include: the 1947 Nuremberg Code developed after the trial of Nazi doctors, and the 1978 Belmont Report issued in response to an unethical Syphilis study conducted on African American men. 

Throughout the decades, groundbreaking advancements in biotechnology have compelled the scientific community to unite in discussion to create new guidelines for their responsible and ethical use. The advent of CRISPR genetic engineering has been met with the same commitment to responsible application of the technology and ethical biomedical conduct.

Tune in to learn about:

·       Historical context of Bioethics

·       Safety concerns with DNA manipulation

·       CRISPR-specific safety issues

·       Ethical challenges with CRISPR gene editing

·       The CRISPR babies scandal

 

Catch up on the previous CRISPR episodes:

·       Ep 35: The first CRISPR Chronicles episode: How CRISPR gene therapy is bringing hope to the world

·       Ep 38: A foundational discussion explaining the secret behind CRISPR gene therapy 

·       Ep 41: A look into the ups and downs of how the CRISPR saga developed

·       Ep 47: The CRISPR Cure for Sickle Cell Disease

·       Ep 50: CRISPR clinical trials 

 

And you may also enjoy: 

Reach out to Irina: gostimskaya@gmail.com

Reach out to Fatu:
www.linkedin.com/in/fatubm
Twitter: @thee_fatu_b
and LoveSciencePodcast@gmail.com

Reach out to Shekerah:
www.linkedin.com/in/shekerah-primus
and LoveSciencePodcast@gmail.com


Music from Pixabay: Future Artificial Intelligence Technology 130 by TimMoor
Music from https://freemusicarchive.org/music/Scott_Holmes: Hotshot by ScottHolmesMusic

Cell and Gene therapy in pets
What are ethical standards in biomedicine?
The Hippocratic Oath
Historical perspective on Ethical guidelines in biomedicine
Genetic Engineering advances from DNA structure discovery to cloning of Dolly the sheep
The Nuremberg Code
The Belmont Report
Safety Concerns relating to DNA manipulation
Asilomar conference
How do we monitor for safety concerns?
Levels of Biosafety standards to protect the public
Safety concerns specifically related to CRISPR technology
Dual-use moratorium prompted by bird flu (H5N1) experiments
Dangers of CRISPR Off-target effects
Dangers of CRISPR double stranded DNA cuts
Dangerous immune response possible with CRISPR gene therapy
Editing germline cells and the CRISPR babies scandal