Dr. Pepper....Really?
Welcome to "Dr. Pepper...Really," where Dr. Gary Pepper—a board-certified endocrinologist and Associate Professor at a major U.S. medical school—delves into the world of metabolic health. Join him as he interviews individuals sharing their personal journeys with metabolic issues and chats with experts in metabolism, nutrition, thyroid disease, diabetes, hormone imbalances, weight management, and more. The show aims to provide you with valuable insights and perspectives from top professionals on common yet critical issues affecting your health and well-being.
Dr. Pepper....Really?
Susie Continues Her Ozempic Journey: Month 3
In this engaging follow-up episode, Susie enters the 14th-week of her journey with Ozempic, highlighting its impact on her health and lifestyle. Initially hesitant about injections, she finds them surprisingly easy and experiences significant health improvements without major side effects, except for an isolated heartburn incident. Remarkably, Susie notes a shift in her eating habits, feeling full sooner and savoring food without overindulging. She's thrilled with a 14-pound weight loss and improved energy levels. Medical check-ups show encouraging results, particularly a notable decrease in her A1C levels, pushing her out of the diabetic range. Susie's commitment to a healthier lifestyle, including smarter food choices and ongoing medication, is evident. The podcast touches on broader issues of medication accessibility and the psychological aspects of weight loss, providing food for thought on this modern approach to an age-old challenge.
Gary Pepper, M.D., an associate professor at a prominent medical school and endocrinologist with 40 years of experience, brings clarity to numerous topics within the field of metabolic health. His view points are unhindered by corporate interests, unlike many other current "thought leaders" in medicine. Dr. Pepper, a dedicated educator, established his homebase website www.metabolism.com in 1996 and has blogged on important topics since then. Not one to be left behind by technology he began podcasting in 2020 with the onset of the pandemic and continues publishing vlogs on YouTube at his channel metabolism123. So whatever your choice in media, you will be gaining fresh insights by tuning in to his opinionated shows or reading his blogs on critical health topics.
<b>[Music]</b><b>Welcome back. Here we are at Dr.</b><b>Pepper, really. We have Susie with us</b><b>again who is on her</b><b>osempic journey and she has told me</b><b>that she's doing well. So Susie, why</b><b>don't you fill us in?</b><b>How are things going? I'd be glad to</b><b>fill you in Dr. Pepper.</b><b>Nice to see you again.</b><b>Things are going very well. When I</b><b>last spoke with you, I had been on</b><b>week three of taking the</b><b>osempic, still at a subtherapeutic</b><b>dose. In other words, taking it but</b><b>not enough to really have</b><b>effects. At the suggestion of my</b><b>doctor, I increased it to 0.5</b><b>milligrams after week four.</b><b>And that's when things really started</b><b>to happen. I am now 14 weeks into</b><b>this, so time goes by</b><b>quickly. And I'm still taking the</b><b>plain five milligrams. Right from the</b><b>beginning, I really</b><b>did not have a problem doing the</b><b>injection. I mentioned last time the</b><b>needle is super tiny.</b><b>Even though I'm a nurse practitioner,</b><b>I don't love injections.</b><b>Never like giving them,</b><b>never like getting them. This is</b><b>really nothing and takes about a</b><b>second to do. Very clear,</b><b>very easy. It's an actual, it looks</b><b>like a pen and you dial up your dose</b><b>and inject it. It takes</b><b>literally a couple of seconds. So</b><b>that part's been great. What's really</b><b>been good is I've been</b><b>feeling very, very well. I know there</b><b>are concerns about</b><b>side effects with osempic,</b><b>including GI things like nausea,</b><b>diarrhea, constipation. And really,</b><b>I've not experienced</b><b>that. I did have one day when out of</b><b>the blue, I had really, really</b><b>intense heartburn and very</b><b>uncomfortable to the point where I</b><b>felt like almost like I had to lay</b><b>down, which is not the</b><b>right thing to do for heartburn</b><b>anyway. But I felt really</b><b>uncomfortable. That</b><b>lasted through the</b><b>evening, through the night, through</b><b>part of the next day. I took a little</b><b>pepcid to help calm it</b><b>down. It went away and it has not</b><b>come back since. So has that kind of</b><b>symptom happened to you</b><b>before where you've had such bad</b><b>heartburn? I mean, are you sensitive</b><b>to coffee or something?</b><b>Actually, yes. In the past it has. I</b><b>take medicine on a</b><b>regular basis for heartburn.</b><b>So it had happened in the past, but</b><b>this was unusual in terms of the</b><b>expense of it and the</b><b>duration of it. Okay. But you said</b><b>that hasn't come back again. You're</b><b>pretty good with that.</b><b>How about things like craving? Do you</b><b>have that? That's been so interesting</b><b>because as I talked</b><b>about in the first one, the first</b><b>time we met, I love food. I love to</b><b>eat. I look forward to</b><b>going out. I look forward to having</b><b>dinner with friends. I've still had</b><b>the feeling of, oh boy,</b><b>I can't wait to eat something, but</b><b>not in so much in the craving way.</b><b>That's been a really</b><b>big noticeable change. So I'll still</b><b>look forward. I think last time I</b><b>talked about having a muffin</b><b>when having coffee with a friend,</b><b>I'll still think this is great. I'm</b><b>going to have coffee in a</b><b>muffin. I'll look forward to it. I'll</b><b>order the muffin. But what I find is</b><b>I eat like a third of</b><b>the muffin and I'm full and I take</b><b>the rest home and I have it for the</b><b>next day. That's a big</b><b>difference as opposed to sitting down</b><b>and saying, here it is. I'm just</b><b>going to eat the whole thing.</b><b>I'm kind of glad about that because I</b><b>did not want to lose sort of the</b><b>pleasure I get from eating</b><b>and food and all the socialization</b><b>with that. Right. Have</b><b>you noticed any change in</b><b>like change in your body shape?</b><b>People talk about their</b><b>face getting thinner or</b><b>they're losing tone in</b><b>their arms or things like that.</b><b>Yes, actually. Probably because I see</b><b>myself every day. I don't notice it</b><b>as much. A few people have</b><b>commented to me that I do seem a</b><b>little thinner. I can tell you I</b><b>weigh myself every week and since</b><b>starting this journey 14 weeks ago,</b><b>I've lost 14 pounds.</b><b>Terrific. And do you overall,</b><b>do you notice how you feel like your</b><b>energy or anything?</b><b>I do. I feel a little more energetic.</b><b>And as you know, it's very</b><b>reinforcing. So if you get on the</b><b>scale Friday morning before doing the</b><b>ozepic, which is my routine, and I</b><b>see, oh, I lost half a pound,</b><b>three quarters of a pound, a pound.</b><b>It's very motivating to want to keep</b><b>doing and doing the</b><b>things that may be working. I'm also</b><b>trying to eat a little bit healthier.</b><b>Sure. Shopping the</b><b>perimeter, like you said, I'm getting</b><b>to know the parameters, we're getting</b><b>to know each other more.</b><b>And, you know, seriously, what I'm</b><b>doing is if I'm in the</b><b>supermarket, I'm not getting</b><b>two kinds of cookies, maybe I'll get</b><b>one and I'll notice I haven't even</b><b>eaten them or I've had one</b><b>and that's more than enough. Really,</b><b>really amazing, huh?</b><b>Okay. And you saw your doctor</b><b>recently so far. And what I did, I</b><b>had my follow up with</b><b>my doctor several times.</b><b>I did and it was a virtual</b><b>appointment. What I did is I went to</b><b>have lab work done</b><b>about five days before the</b><b>appointment. And there was</b><b>improvement. My</b><b>concern was the biggest</b><b>concern was my A1C, which measures</b><b>how your diabetes is going.</b><b>And mine was on the higher</b><b>side. And it now went down. It went</b><b>down to just above normal range</b><b>according to the lab that we're</b><b>using right now. And when I spoke to</b><b>the doctor, she said, I'm not in the</b><b>range of diabetes anymore,</b><b>which was really good. I was just on</b><b>the very edge of that diagnosis. And</b><b>that's what really</b><b>propelled me to think I can't do</b><b>this. I need to make</b><b>changes. That went down.</b><b>Can I interrupt you? But not a lot.</b><b>How many points or half a point? How</b><b>much did it come down?</b><b>Do you know? Did it come down a half?</b><b>I'm trying to think</b><b>about it. I think I went.</b><b>No, it went more than half a point,</b><b>about three quarters of a point.</b><b>Great. And that's a very short period</b><b>of time. So what's your plan?</b><b>What's the next step? My plan is</b><b>that, and I discussed this with the</b><b>doctor, because I think</b><b>it's really important to know that</b><b>this is a medical</b><b>situation. This is not, kind of,</b><b>because everyone talks about ozemphic</b><b>as being almost so trendy. I don't</b><b>see it as trendy for</b><b>me. I see it as something I want to</b><b>be healthy. And so I do things that</b><b>my doctor recommends.</b><b>If I have questions, I'll ask the</b><b>doctor about it. And my choice is to</b><b>continue with what I'm</b><b>doing right now. She said it would be</b><b>fine to increase it if I wanted to,</b><b>but it was also fine</b><b>to keep going at the dose that I'm</b><b>on. And my feeling is if I'm not</b><b>having side effects,</b><b>I am losing weight. The cravings are</b><b>better. And most importantly, my lab</b><b>work is showing that</b><b>hopefully my health is better. I</b><b>would like to continue with what I'm</b><b>doing. She said that if</b><b>about a month goes by and I do not, I</b><b>hit a plateau and don't lose any more</b><b>weight, that I should get</b><b>in touch with her office about</b><b>perhaps repeating a lab and perhaps</b><b>increasing the dose. But right</b><b>now I'm going to stay where I am.</b><b>Have you noticed any change in your</b><b>hair, skin, or nails?</b><b>I would say no. No, I would say</b><b>that's about the same right now. I</b><b>don't see a big difference.</b><b>One thing I can say is that I was</b><b>someone that was constantly running</b><b>to the bathroom everywhere I</b><b>was. I'd be, I have to pee, I have to</b><b>pee. And that's happening less. And</b><b>my doctor said, and</b><b>you know, Dr. Pepe, you're an</b><b>endocrinologist. Maybe you can help</b><b>validate this as well. She</b><b>said that maybe as my sugar level has</b><b>gone down the glucose level, the need</b><b>to urinate has changed.</b><b>I wouldn't expect that. No, not for</b><b>the type of blood sugar issues that</b><b>you had, but maybe you're</b><b>drinking less. You know, you're</b><b>eating less. Yeah, could be. Yeah, it</b><b>could be. How about your mood?</b><b>Did it affect your mood at all? I</b><b>mean, your mood seems pretty good. I think the only effect I see</b><b>is feeling very happy about how it's</b><b>going. It's a little bit going from</b><b>feeling so out of control</b><b>about something to feeling like</b><b>having a little bit more control. And</b><b>I think that can only help</b><b>somebody's mood. And I feel good. It</b><b>makes me feel like we talked about</b><b>the caretaker situation.</b><b>This makes me feel that I'm taking</b><b>care of myself better, which of</b><b>course makes me more able to</b><b>care for other people as well. So my</b><b>mood's been great. How about sleep?</b><b>Any change in your sleeping?</b><b>So far, I don't see a change. I sleep</b><b>relatively well. So I don't see</b><b>myself having a problem with</b><b>sleep. I don't feel excessively</b><b>tired. I wouldn't say I feel like I</b><b>have a little bit more energy.</b><b>So that's a good thing. But I would</b><b>not say my sleep and per se has been</b><b>affected very much.</b><b>All right. I think what we'll want to</b><b>do is catch up with you again in a</b><b>couple of more weeks.</b><b>You said that you're not going to</b><b>increase your dose, but at this rate,</b><b>you know, there's going</b><b>to be further weight loss and it'll</b><b>be great to see how, you</b><b>know, your body's reacting,</b><b>how you're reacting and see how your</b><b>goals may change and maybe your</b><b>lifestyle as well.</b><b>Definitely. Yeah. So you were saying</b><b>that you think that there were a few</b><b>little bumps. What</b><b>were those bumps? They had nothing to</b><b>do with the ozimpic itself. It had to</b><b>do with the system</b><b>around getting the ozimpic. So one</b><b>thing was I was out of town visiting</b><b>my son. I went to use</b><b>the ozimpic pen and perhaps I somehow</b><b>missed the information. It comes with</b><b>four needles. You attach</b><b>a different needle each time. It</b><b>comes with six of those, but there</b><b>are only four doses in each pen.</b><b>Somehow I missed that fact. I was out</b><b>of town, went to use the ozimpic and</b><b>the pen was empty.</b><b>So what I ended up doing was it's a</b><b>little tricky to get sometimes, but I</b><b>use a very well-known</b><b>pharmacy. I was able to contact a</b><b>pharmacy where I was. They actually</b><b>had me go to their setting</b><b>in a hospital because they said the</b><b>hospital pharmacy might be more</b><b>likely to have it.</b><b>So I was able to get it, but that's</b><b>just a little tip. There's four</b><b>doses, even though there's six</b><b>needles. The other bump has to do</b><b>with insurance. I went to get the pen</b><b>refilled. I do it all</b><b>virtually and then I go pick it up,</b><b>but I got an email saying it wasn't</b><b>covered. I had to get</b><b>another pre-authorization. I'm</b><b>currently waiting for the</b><b>pre-authorization.</b><b>The insurance company</b><b>said at the beginning of the calendar</b><b>year, you need to do that. So I am</b><b>hoping I'll have my</b><b>ozimpic by this Friday, but we'll</b><b>see. Okay. Let me run an idea past</b><b>you. I was reading about</b><b>from another doctor that the big</b><b>problem that happens to a lot of</b><b>people is when they</b><b>can't get the medicine, they can't</b><b>afford it, or they decide to stop it</b><b>or something along those</b><b>lines. They gain their weight back.</b><b>The reason that most experts are</b><b>saying, "Well, because you've</b><b>gotten spoiled using an injection</b><b>instead of the self-control that you</b><b>might get if you were on a</b><b>weight watchers or some other</b><b>behavioral type of program," that</b><b>because people using the injections</b><b>that they don't have that, they go</b><b>right back to their old habits. So</b><b>one of the suggestions by</b><b>this particular physician was maybe</b><b>people using injections should only</b><b>use it every other week</b><b>so that on the off week, they know</b><b>that they have to keep an eye on</b><b>their lifestyle and behavior.</b><b>They can't slip back into their old</b><b>bad habits. And maybe that by doing</b><b>it every other week or</b><b>sort of an intermittent schedule,</b><b>that they can combine the</b><b>good part of the injections</b><b>without bringing in the bad part of</b><b>the lack of lifestyle motivation.</b><b>Does that sound at all practical from</b><b>your point of view?</b><b>Yeah. Everything about weight loss is</b><b>so complicated, isn't</b><b>it? And I think my honest</b><b>question is, I'd love to address that</b><b>in the future. Right now,</b><b>I don't know. I'd like to</b><b>continue with what I'm doing. When I</b><b>hopefully lose more weight, and it</b><b>comes down to a question</b><b>of, "Do I keep doing this forever? Do</b><b>I stop it? Do I do it</b><b>intermittently?" I</b><b>think I would think</b><b>about it more then. So I don't know.</b><b>My understanding in</b><b>some of the things I read</b><b>is that it affects a part of your</b><b>brain that has to do with cravings</b><b>and things like that.</b><b>So if that's true, it makes me a</b><b>little worried about what would</b><b>happen if I wasn't taking it</b><b>anymore. On the other hand, maybe</b><b>it's reinforcing enough and every</b><b>other week is a great way to go.</b><b>So I'd like to think about that. You</b><b>raise a very interesting question</b><b>that I don't give a lot of</b><b>thought to. Well, we're all learning</b><b>together. It's a relatively new</b><b>approach to an old problem.</b><b>So thanks again, Susie. To use an</b><b>expression, it's a</b><b>lot of food for thought.</b><b>[laughter]</b><b>Corny. Hey, that's another pun,</b><b>right? Anyway, so great speaking to</b><b>you, and let's arrange</b><b>our next session in a few weeks. Hey</b><b>there. So that about</b><b>wraps up our episode on Susie</b><b>Stotzozimpic in her third month now.</b><b>And I hope you enjoyed it and got</b><b>something out of it. And</b><b>we're very proud of Susie that she's</b><b>doing so well and</b><b>she's very articulate about</b><b>her process and the ups and downs</b><b>that inevitably occur in such a</b><b>situation. And I was recently</b><b>impressed with a news story that I</b><b>saw about people who were using</b><b>Ozimpic and losing their hair.</b><b>And having been an endocrinologist</b><b>for 30 years, it was clear to me that</b><b>this could be a hormonal</b><b>issue that people can run into using</b><b>these powerful</b><b>medications. And also the weight loss</b><b>itself is associated with a lot of</b><b>bodily changes that could impact the</b><b>person in such a way. Hair,</b><b>skin and nails are very sensitive to</b><b>weight loss. So I'm doing a show on</b><b>that and you can find that</b><b>on my YouTube channel Metabolism123.</b><b>And click on our show and subscribe.</b><b>Any little bit helps.</b><b>We're a very small channel and we're</b><b>very well kept secret, which I'd like</b><b>to fix. Thanks a lot.</b><b>[Music]</b>