Maximizing Efficiency and Flexibility in Viral Vector Manufacturing Scale-up
The BioInsights Podcast
Chapters
0:54
Key current challenges in viral vector processing
6:26
Technological advancements in upstream processing
9:13
Ensuring optimal consistency through scale-up/out
12:11
What’s next for transient transfection?
15:23
Enabling viral vector process intensification
20:20
How well are the current range of purification technologies performing?
23:48
How best to improve full/empty/partially full capsid ratio?
27:43
Standardized vector platform processes
30:01
Minimum process parameters needed to build a platform viral vector process
33:16
Automating gene therapy manufacture for rare disease indications
The BioInsights Podcast
Maximizing Efficiency and Flexibility in Viral Vector Manufacturing Scale-up
Mar 02, 2023
Season 2
Episode 1
Denis Kole, Jon Petrone, Marc Bisschops and Nathan Hazi
Four viral vector experts from diverse groups within Pall Corporation’s gene therapy manufacturing organization – Denis Kole, Jon Petrone, Marc Bisschops and Nathan Hazi – join BioInsights to share insights in hot topics for the field, including optimizing upstream process yield and titer, full/empty/partially full capsid separation, and platform process development.
