Navigating genomics and transcriptomics in the immuno-oncology space

Lauren Coyle, Commissioning Editor, Immuno-Oncology Insights, interviews Katie Campbell, Postdoctoral Fellow, Cancer Research Institute, about her current research on genomics, transcriptomics, and spatial profiling to address challenges in the I-O field.

Chapters

• 0:59 Can you tell us a bit about your career in the I-O space so far and what you're currently working on?
• 2:33 Looking at genomics and transcriptomics data, how has this successfully been implemented in I-O so far and what challenges remain to be solved?
• 4:54 How can these challenges be addressed going forward?
• 6:01 How does the integration of spatial profiling data contribute to a better understanding of molecular drivers and cellular interactions?
• 10:03 When it comes to navigating these questions, do you think it is better to start with a clear hypothesis or are there different routes that work better?
• 12:03 In your current research on somatic alterations and antigen-presenting machinery, how do you approach the analysis of HLA genes?
• 14:03 Following that, what strategies have you employed to identify and characterize copy number alterations in the antigen-presenting machinery?
• 15:11 How do you collaborate with experts from different fields, and how has this contributed to the progress of your research?
• 17:54 Finally, what are your main goals and aspirations for the future?