The Cairn Podcast: Marking the Trail for Veterinarians
A Podcast for Veterinarians and Animal Lovers.
We are your centralized resource for veterinary interests, education, and personal development. How we take care of ourselves, each other, patients and pet parents, and how we grow as members of this community - this is what we hope our podcast provides!
The Cairn Podcast: Marking the Trail for Veterinarians
Personalized Medicine
Join us as we embark on an exciting whirlwind tour of personalized medicine in companion animals, and how it may change the future of veterinary medicine as it enables us to focus more on individual patients instead of population medicine assumptions. Before highlighting a recent review article in the Veterinary Clinics of North America (The Role of Personalized Medicine in Companion Animal Cardiology), we discuss nutrigenomics, pharmacogenomics, cancer treatment, allergies, and more, as specific to individual genetic profiles. Hang on and enjoy the ride!
Episode Resources and References:
Rivas VN, Stern JA, Ueda Y. The Role of Personalized Medicine in Companion Animal Cardiology. Vet Clin Small Anim 53 (2023) 1255-1276.
Brown LC, Bobo WV, Gall CA, Müller DJ, Bousman CA. Pharmacomicrobiomics of
Antidepressants in Depression: A Systematic Review. J Pers Med. 2023 Jun 30;13(7):1086. doi: 10.3390/jpm13071086. PMID: 37511699; PMCID: PMC10381387.
Campion DP, Dowell FJ. Translating Pharmacogenetics and Pharmacogenomics to the Clinic: Progress in Human and Veterinary Medicine. Front Vet Sci. 2019 Feb 11;6:22. doi: 10.3389/fvets.2019.00022. PMID: 30854372; PMCID: PMC6396708.
Court MH. Canine cytochrome P-450 pharmacogenetics. Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):1027-38. doi: 10.1016/j.cvsm.2013.05.001. Epub 2013 Jun 13. PMID:23890236; PMCID: PMC3740394.
Irvin MR, Sitlani CM, Floyd JS, Psaty BM, Bis JC, Wiggins KL, Whitsel EA, Sturmer T, Stewart J, Raffield L, Sun F, Liu CT, Xu H, Cupples AL, Tanner RM, Rossing P, Smith A, Zilhão NR, Launer LJ, Noordam R, Rotter JI, Yao J, Li X, Guo X, Limdi N, Sundaresan A, Lange L, Correa A, Stott DJ, Ford I, Jukema JW, Gudnason V, Mook-Kanamori DO, Trompet S, Palmas W, Warren HR, Hellwege JN, Giri A, O'donnell C, Hung AM, Edwards TL, Ahluwalia TS, Arnett DK, Avery CL. Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group. Am J Hypertens. 2019 Nov 15;32(12):1146-1153. doi: 10.1093/ajh/hpz150. PMID: 31545351; PMCID: PMC6856621.
Mealey KL, Martinez SE, Villarino NF, Court MH. Personalized medicine: going to the dogs? Hum Genet. 2019 May;138(5):467-481. doi: 10.1007/s00439-019-02020-w. Epub 2019 Apr 28. PMID: 31032534.
Vaidhya A, Ghildiyal K, Rajawat D, Nayak SS, Parida S, Panigrahi M. Relevance of
pharmacogenetics and pharmacogenomics in veterinary clinical practice: A review. Anim Genet. 2024 Feb;55(1):3-19. doi: 10.1111/age.13376. Epub 2023 Nov 22. PMID: 37990577.
