Forgetting a name or misplacing your keys can be frustrating, but when does memory loss signal something more serious? In this episode, we explain the key differences between normal aging and Alzheimer’s disease. We break down how doctors diagnose Alzheimer’s, the role of biomarkers, and why early detection is crucial for those considering clinical trials.

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References:

Koren, MJ. Toenjes, S. & McKormick, M. (13 April, 2022). Is it Alzheimer's or something else? In MedEvidence! Truth Behind the Data [Podcast]. https://www.buzzsprout.com/admin/1926091/episodes/10248455-is-it-alzheimer-s-or-something-else-ep-11

National Institute on Aging. (8 December, 2022) How is Alzheimer's disease diagnosed? U.S. Department of Health and Human Services, National Institutes of Health. https://www.nia.nih.gov/health/alzheimers-symptoms-and-diagnosis/how-alzheimers-disease-diagnosed

Jack Jr, C. R., Andrews, J. S., Beach, T. G., Buracchio, T., Dunn, B., Graf, A., ... & Carrillo, M. C. (2024). Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup. Alzheimer's & Dementia, 20(8), 5143-5169. https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.13859